Description
Selling lorazepam cas 846-49-1
Selling lorazepam cas 846-49-1
Selling lorazepam cas 846-49-1
Selling lorazepam cas 846-49-1
Lorazepam (also known as Ativan) is a sedative medicine which was first introduced around 1977 for anxiety treatment. It is also used for muscle relaxation. Unwanted side effects include low blood pressure, hangover effects and confusion.
Lorazepam is a benzodiazepine, and it is widely approved and used for status epilepticus (continuous seizures) and anxiety. Benzodiazepines are central nervous system (CNS) depressants, which are medicines that slow down the nervous system and relieve symptoms of anxiety
lorazepam
846-49-1 Usage
Chemical Properties
White Crystalline Solid
Originator
Tavor,Wyeth,Italy,1972
Uses
An anxiolytic, and anticonvulsant. Controlled substance (depressant)
Manufacturing Process
The starting material was 2-amino-2′,5-dichlorobenzophenone which was reacted with hydroxylamine and then with chloroacetyl chloride. The intermediate thus obtained is reacted with methylamine and then with acetic anhydride. To a slightly warm suspension of 3-acetoxy-7-chloro-5-(o-chlorophenyl)-1,3- dihydro-2H-1,4-benzodiazepin-2-one thus obtained was added 4N sodium hydroxide solution with stirring. All the solid dissolved and soon a thick white solid precipitated out. The solid was filtered, washed well with water and recrystallized from ethanol. The product was isolated as a solvate with 1 mol of ethanol. When heated it loses the ethanol of solvation and melts at 166°C to 168°C.
Brand name
Ativan (Baxter Healthcare); Ativan (Biovail); Loraz (Quantum Pharmics).
Therapeutic Function
Tranquilizer
General Description
Lorazepam, 7-chloro-5-(2-chlorophenyl)-3-dihydro-3-hydroxy-2H-1,4-benzodiazepine-2-one(Ativan), is the 2′-chloro derivative of oxazepam. In keepingwith overall SARs, the 2′-chloro substituent increases activity.As with oxazepam, metabolism is relatively rapid anduncomplicated because of the 3-hydroxyl group in the compound.Thus, it also has short half-life (2–6 hours) and similarpharmacological activity.
Check Digit Verification of cas no
Selling lorazepam cas 846-49-1
The CAS Registry Mumber 846-49-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,4 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 846-49:
(5*8)+(4*4)+(3*6)+(2*4)+(1*9)=91
91 % 10 = 1
So 846-49-1 is a valid CAS Registry Number.
846-49-1SDS
SAFETY DATA SHEETS
According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) – Sixth revised edition
Version: 1.0
Creation Date: Aug 19, 2017
Revision Date: Aug 19, 2017
1.Identification
1.1 GHS Product identifier
| Product name | Lorazepam |
|---|
1.2 Other means of identification
| Product number | – |
|---|---|
| Other names | Wypax |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | For industry use only. |
|---|---|
| Uses advised against | no data available |
1.4 Supplier’s details
1.5 Emergency phone number
| Emergency phone number | – |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
Lorazepam powder
Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication.It is used to treat anxiety disorders, trouble sleeping, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy induced nausea and vomiting, as well as for surgery to interfere with memory formation and to sedate those who are being mechanically ventilated. While it can be used for severe agitation, midazolam is usually preferred. It is also used, along with other treatments, for acute coronary syndrome due to cocaine use. Buy pure Lorazepam powder, buy Lorazepam powder, Lorazepam powder supplier, Lorazepam powder for sale, buy Lorazepam
Anxiety
Lorazepam has anxiety-reducing effects and its best-known indication is the short-term management of severe anxiety In the US, the FDA advises against use of benzodiazepines such as lorazepam for longer than four weeks. It is fast acting, and useful in treating fast onset panic anxiety
Lorazepam powder can effectively reduce agitation and induce sleep, and the duration of effects from a single dose makes it an appropriate choice for the short-term treatment of insomnia.
Intravenous diazepam or ativan are first-line treatments for convulsive status epilepticus. Lorazepam is more effective than diazepam in the treatment of status epilepticus
It’s anticonvulsant properties and pharmacokinetic profile, make intravenous use reliable for terminating acute seizures, but induces prolonged sedation Oral benzodiazepines, are occasionally used as long-term prophylactic treatment of resistant absence seizures; because of gradual tolerance to their anti-seizure effects, benzodiazepines such as lorazepam are not considered first-line therapies.
This product is intended for forensic and research applications.
This product has been manufactured and tested to meet ISO17025:2005 and Guide 34:2009 guidelines
This product is intended to be used as an analytical reference standard
Bulk material is available for academic research at qualified institutions; please contact our sales department for pricing
Please read the entire profile before ordering.
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